Making (anti-) sense out of huntingtin levels in Huntington disease
نویسندگان
چکیده
منابع مشابه
Dysfunction of wild-type huntingtin in Huntington disease.
Huntingtin is the protein involved in Huntington disease (HD), an inherited neurodegenerative disease. Research activities have focused on the abnormal functions of mutant huntingtin. However, recent results indicate that wild-type huntingtin has important activities in brain neurons, suggesting that loss of these activities may play a role in HD.
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Int. Union Physiol. Sci./Am.Physiol. Soc.. ESSN: 1548-9221. Visit our website at http://www.the-aps.org/. December by the American Physiological Society, 9650 Rockville Pike, Bethesda MD 20814-3991. © 2003 physiological developments. It is published bimonthly in February, April, June, August, October, and (formerly published as News in Physiological Science) publishes brief review articles on m...
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ژورنال
عنوان ژورنال: Molecular Neurodegeneration
سال: 2015
ISSN: 1750-1326
DOI: 10.1186/s13024-015-0018-7